Massively Parallel Architectures for AI: NETL, Thistle, and Boltzmann Machines

Abstract

Probiotic formulations must contain the right strain(s) in sufficient numbers when administered to confer the desired health benefit. However, significant cell death can occur during freeze-drying and over storage. This study assesses various saccharides for their ability to protect <i>Lactobacillus plantarum</i> cells over freeze-drying and storage, as well as their potential to act as prebiotics. The cryoprotective potential of 10% (m/v) of skimmed milk, inulin, maltodextrin, and sucrose were investigated during freeze-drying. Storage was assessed over 12 weeks at 4 °C and room temperature. Improved cell survival over freeze drying was observed with all the saccharides. However, only maltodextrin and sucrose retained cell viability over storage at 4 °C. Overall, skimmed milk demonstrated the highest survival up to 91%. Despite good cryoprotectant performance, inulin provided the least protection over storage, with <1% cell survival. Prebiotic potential was determined through growth experiments with 2% (m/v) of the saccharides in glucose-free MRS. All saccharides supported cell growth, with sucrose performing best and inulin worst.

Cite

Text

Fahlman et al. "Massively Parallel Architectures for AI: NETL, Thistle, and Boltzmann Machines." AAAI Conference on Artificial Intelligence, 1983. doi:10.1016/j.btre.2021.e00696

Markdown

[Fahlman et al. "Massively Parallel Architectures for AI: NETL, Thistle, and Boltzmann Machines." AAAI Conference on Artificial Intelligence, 1983.](https://mlanthology.org/aaai/1983/fahlman1983aaai-massively/) doi:10.1016/j.btre.2021.e00696

BibTeX

@inproceedings{fahlman1983aaai-massively,
  title     = {{Massively Parallel Architectures for AI: NETL, Thistle, and Boltzmann Machines}},
  author    = {Fahlman, Scott E. and Hinton, Geoffrey E. and Sejnowski, Terrence J.},
  booktitle = {AAAI Conference on Artificial Intelligence},
  year      = {1983},
  pages     = {109-113},
  doi       = {10.1016/j.btre.2021.e00696},
  url       = {https://mlanthology.org/aaai/1983/fahlman1983aaai-massively/}
}