CNN Based Yeast Cell Segmentation in Multi-Modal Fluorescent Microscopy Data
Abstract
We present a method for foreground segmentation of yeast cells in the presence of high-noise induced by intentional low illumination, where traditional approaches (e.g., threshold-based methods, specialized cell-segmentation methods) fail. To deal with these harsh conditions, we use a fully-convolutional semantic segmentation network based on the SegNet architecture. Our model is capable of segmenting patches extracted from yeast live-cell experiments with a mIOU score of 0.71 on unseen patches drawn from independent experiments. Further, we show that simultaneous multi-modal observations of bio-fluorescent markers can result in better segmentation performance than the DIC channel alone.
Cite
Text
Aydin et al. "CNN Based Yeast Cell Segmentation in Multi-Modal Fluorescent Microscopy Data." IEEE/CVF Conference on Computer Vision and Pattern Recognition Workshops, 2017. doi:10.1109/CVPRW.2017.105Markdown
[Aydin et al. "CNN Based Yeast Cell Segmentation in Multi-Modal Fluorescent Microscopy Data." IEEE/CVF Conference on Computer Vision and Pattern Recognition Workshops, 2017.](https://mlanthology.org/cvprw/2017/aydin2017cvprw-cnn/) doi:10.1109/CVPRW.2017.105BibTeX
@inproceedings{aydin2017cvprw-cnn,
title = {{CNN Based Yeast Cell Segmentation in Multi-Modal Fluorescent Microscopy Data}},
author = {Aydin, Ali Selman and Dubey, Abhinandan and Dovrat, Daniel and Aharoni, Amir and Shilkrot, Roy},
booktitle = {IEEE/CVF Conference on Computer Vision and Pattern Recognition Workshops},
year = {2017},
pages = {753-759},
doi = {10.1109/CVPRW.2017.105},
url = {https://mlanthology.org/cvprw/2017/aydin2017cvprw-cnn/}
}