Representational Alignment of Glomeruli Activation in Murine Olfactory Bulb

Abstract

The presence of disease results in the production of odors different from the healthy state, which can be detected by mice. Each odorant generates a unique glomeruli activation pattern in the murine olfactory system. However, these signals differ spatially and temporally across mice and capturing them is labor- intensive. To optimize the process, glomeruli activation patterns for many odor- ants could be mapped from a reference animal imaged on all available odorants to target animals imaged on a subset of odorants. In our initial approach to develop this method, we align the glomeruli activation patterns for 11 odorants between 2 mice using the optimal transport Sinkhorn algorithm.

Cite

Text

Agarwal et al. "Representational Alignment of Glomeruli Activation in Murine Olfactory Bulb." ICLR 2025 Workshops: Re-Align, 2025.

Markdown

[Agarwal et al. "Representational Alignment of Glomeruli Activation in Murine Olfactory Bulb." ICLR 2025 Workshops: Re-Align, 2025.](https://mlanthology.org/iclrw/2025/agarwal2025iclrw-representational/)

BibTeX

@inproceedings{agarwal2025iclrw-representational,
  title     = {{Representational Alignment of Glomeruli Activation in Murine Olfactory Bulb}},
  author    = {Agarwal, Vivek kumar and Manasson, Julia and Garrido-Czacki, Mario H. and Sucholutsky, Ilia},
  booktitle = {ICLR 2025 Workshops: Re-Align},
  year      = {2025},
  url       = {https://mlanthology.org/iclrw/2025/agarwal2025iclrw-representational/}
}