ML Anthology

Cortical Cells Should Fire Regularly, but Do Not

William R. Softky, Christof Koch
NeCo 1992 pp. 643-646
doi:10.1162/NECO.1992.4.5.643 /neco/1992/softky1992neco-cortical/

Abstract

When a typical nerve cell is injected with enough current, it fires a regular stream of action potentials. But cortical cells in vivo usually fire irregularly, reflecting synaptic input from presynaptic cells as well as intrinsic biophysical properties. We have applied the theory of stochastic
\nprocesses to spike trains recorded from cortical neurons (Tuckwell 1989) and find a fundamental contradiction between the large interspike variability observed and the much lower values predicted by well-accepted biophysical models of single cells.

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Text

Softky and Koch. "Cortical Cells Should Fire Regularly, but Do Not." Neural Computation, 1992. doi:10.1162/NECO.1992.4.5.643

Markdown

[Softky and Koch. "Cortical Cells Should Fire Regularly, but Do Not." Neural Computation, 1992.](https://mlanthology.org/neco/1992/softky1992neco-cortical/) doi:10.1162/NECO.1992.4.5.643

BibTeX

@article{softky1992neco-cortical,
  title     = {{Cortical Cells Should Fire Regularly, but Do Not}},
  author    = {Softky, William R. and Koch, Christof},
  journal   = {Neural Computation},
  year      = {1992},
  pages     = {643-646},
  doi       = {10.1162/NECO.1992.4.5.643},
  volume    = {4},
  url       = {https://mlanthology.org/neco/1992/softky1992neco-cortical/}
}