Changes in GABAB Modulation During a Theta Cycle May Be Analogous to the Fall of Temperature During Annealing
Abstract
Changes in GABABmodulation may underlie experimentally observed changes in the strength of synaptic transmission at different phases of the theta rhythm (Wyble, Linster, & Hasselmo, 1997). Analysis demonstrates that these changes improve sequence disambiguation by a neural network model of CA3. We show that in the framework of Hopfield and Tank (1985), changes in GABABsuppression correspond to changes in the effective temperature and the relative energy of data terms and constraints of an analog network. These results suggest that phasic changes in the activity of inhibitory interneurons during a theta cycle may produce dynamics that resemble annealing. These dynamics may underlie a role for the theta cycle in improving sequence retrieval for spatial navigation.
Cite
Text
Sohal and Hasselmo. "Changes in GABAB Modulation During a Theta Cycle May Be Analogous to the Fall of Temperature During Annealing." Neural Computation, 1998. doi:10.1162/089976698300017539Markdown
[Sohal and Hasselmo. "Changes in GABAB Modulation During a Theta Cycle May Be Analogous to the Fall of Temperature During Annealing." Neural Computation, 1998.](https://mlanthology.org/neco/1998/sohal1998neco-changes/) doi:10.1162/089976698300017539BibTeX
@article{sohal1998neco-changes,
title = {{Changes in GABAB Modulation During a Theta Cycle May Be Analogous to the Fall of Temperature During Annealing}},
author = {Sohal, Vikaas S. and Hasselmo, Michael E.},
journal = {Neural Computation},
year = {1998},
pages = {869-882},
doi = {10.1162/089976698300017539},
volume = {10},
url = {https://mlanthology.org/neco/1998/sohal1998neco-changes/}
}