Self-Organization of Hebbian Synapses in Hippocampal Neurons

Abstract

We are exploring the significance of biological complexity for neuronal computation. Here we demonstrate that Hebbian synapses in realistical(cid:173) ly-modeled hippocampal pyramidal cells may give rise to two novel forms of self -organization in response to structured synaptic input. First, on the basis of the electrotonic relationships between synaptic contacts, a cell may become tuned to a small subset of its input space. Second, the same mechanisms may produce clusters of potentiated synapses across the space of the dendrites. The latter type of self-organization may be functionally significant in the presence of nonlinear dendritic conduc(cid:173) tances.

Cite

Text

Brown et al. "Self-Organization of Hebbian Synapses in Hippocampal Neurons." Neural Information Processing Systems, 1990.

Markdown

[Brown et al. "Self-Organization of Hebbian Synapses in Hippocampal Neurons." Neural Information Processing Systems, 1990.](https://mlanthology.org/neurips/1990/brown1990neurips-selforganization/)

BibTeX

@inproceedings{brown1990neurips-selforganization,
  title     = {{Self-Organization of Hebbian Synapses in Hippocampal Neurons}},
  author    = {Brown, Thomas H. and Mainen, Zachary F. and Zador, Anthony M. and Claiborne, Brenda J.},
  booktitle = {Neural Information Processing Systems},
  year      = {1990},
  pages     = {39-45},
  url       = {https://mlanthology.org/neurips/1990/brown1990neurips-selforganization/}
}