Cholinergic Modulation May Enhance Cortical Associative Memory Function
Abstract
Combining neuropharmacological experiments with computational model(cid:173) ing, we have shown that cholinergic modulation may enhance associative memory function in piriform (olfactory) cortex. We have shown that the acetylcholine analogue carbachol selectively suppresses synaptic transmis(cid:173) sion between cells within piriform cortex, while leaving input connections unaffected. When tested in a computational model of piriform cortex, this selective suppression, applied during learning, enhances associative memory performance.
Cite
Text
Hasselmo et al. "Cholinergic Modulation May Enhance Cortical Associative Memory Function." Neural Information Processing Systems, 1990.Markdown
[Hasselmo et al. "Cholinergic Modulation May Enhance Cortical Associative Memory Function." Neural Information Processing Systems, 1990.](https://mlanthology.org/neurips/1990/hasselmo1990neurips-cholinergic/)BibTeX
@inproceedings{hasselmo1990neurips-cholinergic,
title = {{Cholinergic Modulation May Enhance Cortical Associative Memory Function}},
author = {Hasselmo, Michael E. and Anderson, Brooke P. and Bower, James M.},
booktitle = {Neural Information Processing Systems},
year = {1990},
pages = {46-52},
url = {https://mlanthology.org/neurips/1990/hasselmo1990neurips-cholinergic/}
}