ML Anthology

Hidden Markov Models for Human Genes

Pierre Baldi, Søren Brunak, Yves Chauvin, Jacob Engelbrecht, Anders Krogh
NeurIPS 1993 pp. 761-768
/neurips/1993/baldi1993neurips-hidden/

Abstract

Human genes are not continuous but rather consist of short cod(cid:173) ing regions (exons) interspersed with highly variable non-coding regions (introns). We apply HMMs to the problem of modeling ex(cid:173) ons, introns and detecting splice sites in the human genome. Our most interesting result so far is the detection of particular oscilla(cid:173) tory patterns, with a minimal period ofroughly 10 nucleotides, that seem to be characteristic of exon regions and may have significant biological implications.

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Text

Baldi et al. "Hidden Markov Models for Human Genes." Neural Information Processing Systems, 1993.

Markdown

[Baldi et al. "Hidden Markov Models for Human Genes." Neural Information Processing Systems, 1993.](https://mlanthology.org/neurips/1993/baldi1993neurips-hidden/)

BibTeX

@inproceedings{baldi1993neurips-hidden,
  title     = {{Hidden Markov Models for Human Genes}},
  author    = {Baldi, Pierre and Brunak, Søren and Chauvin, Yves and Engelbrecht, Jacob and Krogh, Anders},
  booktitle = {Neural Information Processing Systems},
  year      = {1993},
  pages     = {761-768},
  url       = {https://mlanthology.org/neurips/1993/baldi1993neurips-hidden/}
}