Morphogenesis of the Lateral Geniculate Nucleus: How Singularities Affect Global Structure
Abstract
The macaque lateral geniculate nucleus (LGN) exhibits an intricate lamination pattern, which changes midway through the nucleus at a point coincident with small gaps due to the blind spot in the retina. We present a three-dimensional model of morphogenesis in which local cell interactions cause a wave of development of neuronal re(cid:173) ceptive fields to propagate through the nucleus and establish two distinct lamination patterns. We examine the interactions between the wave and the localized singularities due to the gaps, and find that the gaps induce the change in lamination pattern. We explore critical factors which determine general LGN organization.
Cite
Text
Tzonev et al. "Morphogenesis of the Lateral Geniculate Nucleus: How Singularities Affect Global Structure." Neural Information Processing Systems, 1994.Markdown
[Tzonev et al. "Morphogenesis of the Lateral Geniculate Nucleus: How Singularities Affect Global Structure." Neural Information Processing Systems, 1994.](https://mlanthology.org/neurips/1994/tzonev1994neurips-morphogenesis/)BibTeX
@inproceedings{tzonev1994neurips-morphogenesis,
title = {{Morphogenesis of the Lateral Geniculate Nucleus: How Singularities Affect Global Structure}},
author = {Tzonev, Svilen and Schulten, Klaus and Malpeli, Joseph G.},
booktitle = {Neural Information Processing Systems},
year = {1994},
pages = {133-140},
url = {https://mlanthology.org/neurips/1994/tzonev1994neurips-morphogenesis/}
}